Nearly half of women who received depotmedroxyprogesterone acetate (DMPA) experienced a significant decrease in bone mineral density (BMD) of the hip bone or lower spine within 2 years after starting this contraceptive, which was published in A recent research report in Obstetrics and gyneco] ogy concluded. The study revealed for the first time that the use of DA for smoking, low-calcium intake and women who have never had children may be at the highest risk of bone loss.
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